Safety of 100 µg venom immunotherapy rush protocols in children compared to adults

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Safety of 100 µg venom immunotherapy rush protocols in children compared to adults

BACKGROUND There is a paucity of studies examining the safety of venom immunotherapy (VIT) in children. We aimed to assess the incidence of anaphylactic side effects during rush VIT in a cohort of pediatric patients and adult controls. METHODS 72 consecutive cycles of VIT-buildup in 71 children/adolescents aged 7-17 years were retrospectively evaluated and compared to an adult control group (...

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Safety of Ultrarush Venom Immunotherapy: Comparison Between Children and Adults.

BACKGROUND The ultrarush protocol is an attractive approach in the buildup phase of venom immunotherapy (VIT-UR). However, the degree of risk of VIT-UR in children remains unknown. The objective of this study was to compare the safety of VIT-UR in children and adults. METHODS We performed a study based on prospectively gathered medical records of children and adults with hymenoptera venom all...

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Rush hymenoptera venom immunotherapy is efficacious and safe.

BACKGROUND Although rapid venom immunotherapy (VIT) protocols have been shown to be safe and effective, this issue has not yet been clarified in Turkey. OBJECTIVE The aim of this study was to evaluate the side effects of rush VIT as well as early clinical and immunological responses in patients with a venom allergy. METHODS Eighteen patients who had a history of severe systemic reactions af...

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Laboratory markers of mast cell and basophil activation in monitoring rush immunotherapy in bee venom-allergic children.

AIM To evaluate markers of mast cell and basophil activation in children undergoing the initial phase of honeybee venom immunotherapy (VIT). PATIENTS & METHODS Five children (four boys and one girl) aged 9.5-18 years with severe systemic bee sting reactions and confirmed IgE-mediated allergy were enrolled. Plasma and urine concentrations of 9α,11β-PGF2 and serum tryptase levels were measured ...

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Rush immunotherapy for wasp venom allergy seems safe and effective in patients with mastocytosis.

BACKGROUND Patients with mastocytosis and wasp venom allergy (WA) may benefit from venom immunotherapy (VIT). However, fatal insect sting reactions have been described in mastocytosis patients despite previous immunotherapy. We investigated the safety and efficacy of (rush) VIT in patients with mastocytosis and WA. OBJECTIVE To investigate the safety and efficacy of (rush) VIT in patients wit...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2017

ISSN: 1710-1492

DOI: 10.1186/s13223-017-0204-y